Pan-Cancer Overview

Analysis of somatic variants disrupting validated N-linked glycosylation sequons (TCGA Pan-Cancer Atlas)

Unique Genes Affected

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Across all projects
Total Loss Events

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Total variant occurrences
Unique Patients/Cases

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With glycan loss variants
Top Impacted Gene

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Total Cohort Patients

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Patients in active cohort

Top Mutation Hotspots

Highest relative patient frequency of validated site disruptions

Disruption Mechanism

How acceptor sequons are abolished

Mutation Lollipop Plot for CDH1

Protein mutation frequency by position (Loss, Gain, and Other background variants)

Multi-Omics Profile:

Mutation Locations for CDH1

Distribution of sequon loss events by position on protein (click on any gene in the chart above to inspect its sites)
0 events

Impact across Cancer Projects

Loss frequency sorted by TCGA project

Detailed Loss Events

Showing raw mutation logs and disruption details
0 events found
Gene Project Case ID Position Sequon Variant Class Mechanism HGVSp
Loading sequon loss events...